Search results for "Fetal alcohol syndrome"
showing 8 items of 8 documents
Los trastornos oculares del espectro alcohólico fetal
2020
Este artículo se encuentra disponible en la siguiente URL: https://www.elsevier.es/es-revista-archivos-sociedad-espanola-oftalmologia-296-articulo-los-trastornos-oculares-del-espectro-S0365669119303508 Preprint
Stippled epiphyses in fetal alcohol syndrome.
1990
We report on punctate epiphyseal calcifications (stippled epiphyses) in the fetal alcohol syndrome and present the differential diagnosis of chondrodysplasia punctata. A literature survey shows that epiphyseal calcifications accompanying alcoholic embryopathy are regularly located in the lower limbs and rarely found in the upper extremities.
Heat shock factor 2 is a stress-responsive mediator of neuronal migration defects in models of fetal alcohol syndrome
2014
Fetal alcohol spectrum disorder (FASD) is a frequent cause of mental retardation. However, the molecular mechanisms underlying brain development defects induced by maternal alcohol consumption during pregnancy are unclear. We used normal and Hsf2-deficient mice and cell systems to uncover a pivotal role for heat shock factor 2 (HSF2) in radial neuronal migration defects in the cortex, a hallmark of fetal alcohol exposure. Upon fetal alcohol exposure, HSF2 is essential for the triggering of HSF1 activation, which is accompanied by distinctive post-translational modifications, and HSF2 steers the formation of atypical alcohol-specific HSF1–HSF2 heterocomplexes. This perturbs the in vivo bindi…
Mediterranean diet and prudent diet are both associated with low circulating esterified 3-hydroxy fatty acids, a proxy of LPS burden, among older adu…
2021
Background LPS-type endotoxins, naturally found in the gut microbiota, are recognized as triggers of inflammation and emerge as detrimental factors of healthy aging. Nutrition represents a promising strategy to reduce LPS burden, yet little is known about the relation of diet to circulating LPS concentrations. Objective The aim was to evaluate the associations between food groups, dietary patterns, and circulating 3-hydroxy fatty acids (3-OH FAs), a proxy of LPS burden. Methods In a cross-sectional study of 698 French older community-dwelling individuals, 3-OH FA concentrations were measured by LC-tandem MS. Dietary patterns were determined using food-frequency questionnaires. Adherence to …
Opolskie voivodeship secondary school students’ knowledge about fetal alcohol syndrome and its determinants
2019
Background: Alcohol consumption during pregnancy may result in a wide range of morphological and neurodevelopmental abnormalities, most notably fetal alcohol syndrome (FAS). Objectives: To evaluate: (1) Opolskie Voivodeship high school students’ level of knowledge on the subject of FAS (2) the factors contributing to this level of knowledge (3) sources of information about FAS which are accessible and preferred by secondary school students. Materials and methods: The study was conducted in 2018 among 228 adult students of Opole secondary schools. The authors used a diagnostic survey based on original questions they developed for the study. The students’ knowledge was assessed using a four-l…
Mechanisms of protein expression in the rat optic nerve: Modifications by alcohol exposure
2005
espanolObjetivos: Nuestros trabajos previos han demostrado que el consumo abusivo de etanol durante la gestacion induce retraso en el desarrollo y alteraciones estructurales en los ojos y en la vision (Pinazo-Duran et al., Teratology 93; Eur J Ophthalmol 97; Stromland and Pinazo-Duran, Teratology 94; Alcohol Alcoholism 02). Nos proponemos estudiar a un nivel celular y molecular si el etanol modifica la expresion de proteinas marcadoras del desarrollo glial durante los estadios pre- y postnatal de la rata, que puedan contribuir a la dismorfogenesis del nervio optico. Metodo: Para estudiar las acciones del etanol sobre el desarrollo del nervio optico de ratas sometidas a un proceso de alc…
Neuropsychiatric aspects of fetal alcohol syndrome in children.
2011
College students’ attitudes towards prohealth behavior and alcohol consumption during pregnancy planning and pregnancy
2021
Background: Alcohol is one of the most commonly used psychoactive substances among students. Aim of the study: This study aimed to examine the level of pro-health behaviors among college students, and their opinions on alcohol consumption during pregnancy planning and pregnancy. Material and methods: This study was conducted in 2018 among 228 adult students in Opole secondary schools. Diagnostic surveys were used, which included the Health Behavior Inventory (HBI) and a questionnaire developed by the authors. Results: Forty-six percent (n = 105) of the 228 students presented with very low levels of pro-health behaviors and 57.46% (n = 131) of students endorsed alcohol intoxication or abuse …